Reproductive Genetics
Genetics is thought to play a role in up to 10% of infertility concerns or recurrent pregnancy losses in couples. As a woman’s age rises, so does her likelihood of discovering genetic abnormalities. During the first trimester of pregnancy, most embryos with an erroneous number of chromosomes fail to implant or miscarry. Many of those couples could benefit from genetic testing techniques in their desire to start a family. Our comprehensive range of genetic testing services can significantly improve your chances of conceiving.
PGT - Monogenic
PGT-M entails screening embryos for certain monogenic illnesses such as Thalassemia, haemophilia, and muscular dystrophy. It aids couples who have a family history of these disorders or who have had a child with one of these disorders to have a kid who is not affected. This specific monogenic disease is checked in all embryos created using Assisted Reproductive Technology (ART). To have a disease-free child, only unaffected or career embryos are transferred. This can also be used in conjunction with PGT-A to boost success rates even more.
ERA (Endometrial Receptivity Array)
ERA is a genetic test that determines the level of endometrial receptivity during the implantation window. The exact time period during which an embryo must be placed into a woman’s uterus in order to establish a successful pregnancy is determined by the ERA.
PGT - Aneuploidy
PGT-A is a genetic test used on embryos to detect aneuploidy or numerical chromosomal abnormalities. This test is done on embryos before they are implanted in the uterus. Those embryos free of chromosomal aneuploidy can be identified for selective transfer by analyzing all embryos created during an IVF treatment cycle. As a result, the number of pregnancies per transfer has increased while the number of miscarriages has reduced.
PGT - Structural Rearrangement
PGT-SR is a test that looks for patients who have chromosomal rearrangements (structures that hold our genetic material is not of normal size or arrangement). These folks run the risk of having an imbalanced chromosomal structure in their embryos. Embryos of this type are not viable and can lead to numerous miscarriages. PGT-SR detects such precise rearrangements in embryos and can aid in the selection of healthy embryos for transfer.
Who is this for?
For patients with good morphological quality embryos who have suffered implantation failure (at least 3 failed embryo transfers for women younger than 37 years or 2 failed transfers in women older than 37 years)
For patients who have a normal uterus and a normal endometrial thickness (less than 6mm) and no obvious issues.
