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Intrauterine Insemination (IUI)

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Intrauterine Insemination (IUI)

Intrauterine Insemination (IUI)

Intrauterine insemination, or IUI, is an assisted reproductive technology (ART) procedure intended to aid couples who are having difficulty conceiving. The treatment involves injecting sperm from the husband or a donor directly into the female partner’s uterus. Artificial Insemination is another name for IUI.

Who is recommended for IUI?

Sexual disorders

IUI is seen to be the best course of action for couples whose male spouse has been diagnosed with an infertility-related condition, such as erectile dysfunction, low sperm count, or abnormalities in sperm shape and mobility. Using the IUI method, a physician directly injects a man's sperm into a woman's uterus to help her conceive. By addressing some of the causes of infertility and injecting sperm into mature eggs during ovulation, IUI seeks to raise the likelihood of becoming pregnant.

Ovulation Disorders

IUI is a viable option for women who struggle with ovulation abnormalities and infertility that doesn't make sense. Initially, ovarian stimulation medicines are administered to a patient in an effort to boost and enhance the fertility of the woman, something that may not be possible without medication.
Ovulation Disorders
Inhospitable cervical conditions cervical

Inhospitable cervical conditions

In-vitro fertilization (IUI) is a method of treating reproductive health concerns resulting from abnormalities or cervical stenosis by directly inserting sperm into the uterus. Reduced chances of conception could result from sperm having a harder time accessing the egg through a larger cervix. In order to increase the volume of sperm available to meet the waiting egg, IUI works by directly putting sperm into the uterus, avoiding the cervix. Before pursuing alternative fertility treatments, you might give IUI another go if you are still unable to conceive.

Grade I endometriosis with patent tubes

IUI helps address reproductive health issues brought on by abnormalities or cervical stenosis by injecting sperm straight into the uterus. The likelihood of fertilization may be decreased if the cervix is thicker because it may be harder for sperm to access the egg. By injecting sperm directly into the uterus instead of via the cervix, intrauterine insemination (IUI) increases the quantity of sperm available to fertilize the waiting egg. You can try IUI again before moving on to other fertility treatments if you are still unable to conceive.
Patient tubes
Age of the female partner

Age of the female partner

Age is an important factor to take into account when prescribing IUI treatment to a patient. Experts in fertility believe in vitro stimulation (IUI) to be the first-line treatment for age-related infertility because fertility medications are utilized to boost egg production prior to treatment. Conversely, an older age may negatively affect the effectiveness of IUI. Research indicates that individuals over 40 have reduced IUI success rates. It makes sense that a woman would naturally have fewer eggs as she ages.

Male factor subfertility such as low sperm count and motility

IUI treatment may be beneficial in cases of infertility if there is male subfertility. One effective treatment for male infertility is IUI, which has a high success rate. Among the most common male infertility issues are retrograde ejaculation, low sex drive, and erectile dysfunction. IUI simplifies the procedure by directly implanting the sperm into the woman's uterus. By avoiding the cervix and vagina, IUI gives the sperm an advantage when it comes to accessing the egg for fertilization.
low sperm count and motility
Prior to the actual ‘IUI procedure,’ intrauterine insemination is divided into a number of steps. These steps are as follows:

IUI Process

01

Counseling and Treatment

IUI treatment can be physically and emotionally draining for a couple. Couples that seek counselling from Crysta Counselors gain a better understanding of the therapeutic process.
02

Stimulation and Monitoring

On the second day of the menstrual cycle, the female partner receives medication to promote the development of follicles in the ovary. Up to day six, or until the doctor decides it's no longer necessary, stimulation is continued.
03

The Ovulation Cycle Is Being Monitored

From day 9 through day 12 or 13, stimulation causes the production of follicles, which must be monitored for growth and size. The professional determines the scan interval based on the requirements.
04

Trigger for ovulation

Day 12: An hCG injection is administered to the female partner to trigger ovulation after the follicles reach the appropriate size. Within 36 hours after the trigger being activated, ovulation takes place.
05

IUI

On day 13, a scan is done to check whether ovulation has taken place. In case the ovulation has occurred, the IUI is scheduled for the same day or on day 14.

IUI Success Rate

An IUI procedure’s success is determined by a number of factors, including the age of the couples, the type of fertility problem, and any pre-existing medical disorders. IUI, on the other hand, has a success rate of roughly 10-20% in most circumstances, and even with some pre-existing issues, it can achieve an 8-16% success rate with optimal fertility treatment.

  • Moderate to severe endometriosis
  • Poor sperm count and motility
  • Severe damage to fallopian tubes
IUI may not be successful in such instances, and the couple is advised to pursue IVF treatment for the best results.
IUI is a reasonably safe technique with few hazards, which are listed below:

Risks associated with IUI

Infection
An infection can occur during the IUI process, however it is rare. It is possible that vaginal germs will enter the uterus during catheter-assisted sperm insemination. These infections do, however, represent a very small percentage of cases—roughly 0.3 percent. Appropriate sterilization lowers the infection rate at the IVF facility.
Blood Spotting
During the IUI technique, a tiny amount of vaginal bleeding may occur as a result of the catheter being inserted into the uterus. It happens when the insertion of the catheter causes inflammation in the cervical and vaginal tissues of the uterus. However, this has no appreciable detrimental effect on the likelihood of conception.
Multiple Pregnancy
Multiple pregnancies are not a risk of the IUI technique itself. However, when used in conjunction with ovulation induction medication, there is a substantial risk of multiple pregnancies. Ovulation induction can sometimes result in the release of two or more mature eggs, which can lead to multiple pregnancies.
Ovarian Hyperstimulation Syndrome
Sometimes, using fertility medication before an IUI procedure might lead to the ovaries becoming overstimulated. In such cases, a large number of ova (eggs) are stimulated to mature and are ejected simultaneously. Common adverse effects of hyperstimulation include fluid accumulation in the belly, discomfort, and ovarian expansion.
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